Vitamin B1, also known as thiamine, is essential for converting food into cellular energy and protecting the nervous system — yet deficiency is frequently overlooked. Because less than 1% of thiamine circulates in the blood, standard lab tests often fail to detect low levels, leaving many people unaware of the cause behind a range of persistent symptoms. Here are 12 physical signs that may indicate your body needs more of this critical nutrient.

In brief
- —Standard blood tests often miss thiamine deficiency
- —12 symptoms range from nerve pain to brain fog
- —Alcohol, sugar and some medications deplete B1
Why thiamine is hard to detect — and easy to deplete
Thiamine plays a central role in energy metabolism, helping cells convert carbohydrates, fats, and proteins into usable fuel. It also maintains the myelin sheath — the protective coating around nerve fibers — allowing electrical signals to travel correctly between the brain and the rest of the body.

